White spot lesions (WSL) around orthodontic brackets are a well-known complication during and after orthodontic treatment. The aim of this in-vitro study was to determine if we can minimize or prevent this phenomenon by using different bonding systems and if we can re-mineralize the enamel using different fluoride enriched varnishes.
Extracted intact premolars were used- orthodontic brackets were bonded using a composite based bonding system, High Q Bond and a glass-ionomer bonding system, Fuji Ortho. Following brackets bonding, the teeth were placed in a cariogenic solution (pH around 4.0) for a period of 14 days. The effect of the cariogenic solution was observed using SEM at enlargements of 1000X. After demineralization process, two kinds of varnishes, MI varnish and Pro fluoride varnish. The effect of the varnish application was dem-onstrated using SEM pictures and chemical analyses of the treated enamel. The results showed that after bonding with glass-ionomer based cement no demineralization occurred around the brackets, while around brackets bonded with composite based cement a sig-nificant demineralization was observed. Application of fluoride varnishes remineralized the surface enamel and a significant amount of fluoride was found in the surface enamel.

Introduction: Dermatological bullous diseases have visible signs in the oral cavity. The study is aimed at early detection of oral le-sions, to link them to the presence or not of apparent skin disorders affecting the quality of the patient’s lifestyle. Patient awareness of coexistence between dermatological concerns and the presence of oral lesions should be the starting point of every dentist during the intraoral examination, after drying of the mucous membranes and gingiva.
Materials and Methods: The study includes patients randomly presented: patients at the University Clinic Albanian University and patients in the Dermatology Department, Qendra Spitalore Universitare “Nёnё Tereza”, during the period between november 2017 and january 2018. Patients were evaluated according to the Dermatological Life Quality Index (ICJD) and the presence of oral lesions in the oral cavity.
Results: Oral lesions reported in the patients appear to be more commonly occurring in female patients than in male patients over 40 years of age. Oral buccal mucosa areas are more affected than gingival area, palatum and tongue areas.
Conclusions: Detection of disorders during oral routine examination is the beginning to follow the evolution of these dermatologi-cal bullous diseases, as the further prognosis also depends on the moment of detection and awareness of the initial existence of the disease.
Keywords: ICJD; Bullous Diseases; Oral Mucous Membranes; Gingiva.