Coronavirus (CoV) infections are emerging respiratory viruses and are known to cause illness ranging from the common cold to severe acute respiratory syndrome (SARS) [1]. The name “coronavirus” is derived from the Latin word Corona and the Greek word korṓnē, which means crown. Novel Coronavirus (COVID-19) have been identified by Chinese authorities, and this was declared by the World Health Organization on January 9, 2020. The virus is related to a pneumonia outbreak in Wuhan City, Hubei Province, China. The current outbreak of novel coronavirus (COVID-19) in Wuhan City, Hubei Province, China, has emerged as a global outbreak and significant public health issue [2]. On January 30, 2020, the World Health Organization (WHO) declared COVID-19 a public health emergency of international concern (PHEIC). Origin of the infection (COVID-19) is currently unknown, but 66% of the initially infected patients (27/41) were directly exposed to the Huanan seafood market [3]. As of March 28, 2020, novel coronavirus (COVID-19) has spread to more than 170 countries with confirmed novel coronavirus cases have crossed 530,000, while more than 24,000 deaths have been reported across the world as Europe becomes the new epicenter of coronavirus. More than 80% of the global COVID-19 cases are currently outside China [4]. According to current data, the fatality rate (cumulative deaths divided by cumulative cases) of COVID-19 is 0.39% to 4.05%.

Introduction: Denosumab is a human monoclonal antibody. The goal of the drug is to stop bone loss. Before a dental surgery, it is important to know the benefit-risk ratio of the anti-resorptive drugs. When it comes to implant treatment, Denosumab has side effects, such as osteonecrosis of the jaws.
Objectives: Protocol for the dentist before, during and after the placement of implants and oral surgery. In patients medicated with. Epidemiology of ONJ. As a final objective, the treatment of implants was compared in patients treated with two similar drugs: Bisphosphonates and Denosumab.
>Materials and Methods: The search was carried out through: Medline, Google academic, Cochrane, Scielo and Pubmed.
Results and Discussion: In this section the proposed objectives have been developed. It is essential to have a careful clinical history, in addition to a cooperation with the patient’s specialist doctors, before the surgical treatment of implants. The professional must establish an early diagnosis of ONJ, with a correct treatment plan. Radiographic follow-up in oral surgery is crucial to be able to review the signs of osseointegration of the implants and the possible signs of osteonecrosis of the bone. The most common cases of osteonecrosis are given by oral surgery with several comorbidities that participate in the process of bone deterioration. The main advantage of Denosumab is its reversible effect: it does not persist for long periods of time in the bone.
Conclusion: Many studies concluded that the diagnosis of osteonecrosis can be given after intake of drugs such as Denosumab or bisphosphonates. Osteonecrosis is a complication of multifactorial origin and it is necessary to know both the pathology and the clinical protocols of action to perform the best possible a dental implant treatment.
Keywords: Denosumab; Osteonecrosis; Protocols and Odontology; Dental Implants and Oral Surgery

Widely used in Medicine, botulinum toxin type A presents your cosmetic or therapeutic use, has been increasing its indications. In Dentistry, it is indicated in temporomandibular disorders, orofacial dystonia, bruxism, dental clenching, masseteric hypertrophy, sialorrhea, facial asymmetry of muscular origin, gummy smile and lip asymmetries that can cause severe gum exposure. Recently, it has been shown the prophylactic application of botulinum toxin in patients after rehabilitation on dental implants, reducing masticatory forces and protecting the prostheses and implants. The purpose of this article is to present the case of a patient with excessive gingival exposure and aesthetic disharmony after dental implant rehabilitation in the anterior region, whose tooth loss occurred due to a previous traffic accident. After the conclusion of the rehabilitation treatment, the patient has received the botulinum toxin application to reduce gingival display and to minimize the exposure of cervical area of the prostheses implants.
Keywords: Botulinum Toxins; Dental Aesthetics; Dental Implants; Smiling

The vital tooth bleaching technique has been widely used in the dental clinic. Care is usually taken, as in the choice of bleaching gel concentration and in the confection of the trays, avoiding, respectively, the dentin hypersensitivity and trauma by tray excess over the marginal gingival region. However, the action of the bleaching gel over the periodontal tissues has not been much explored. We present in this article a clinical case of gingival erosions due to home dental bleaching, using the 10% carbamide peroxide gel, which healed with the cessation of treatment. We also highlight about to the precautions that should be taken in the making of molds and the use of whiteners.
Keywords: Tooth Bleaching; Gingiva; Oral Diagnosis; Wounds and Injuries